Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling
February 09, 2010 (Albany, N.Y., USA )- -INTiDYN founder Phillip J. Albrecht joins researchers from Albany Medical College, the Wadsworth Center, RPI, and other institutions in this study of how certain opioids reduce pain. In the study, the researchers show that after activating certain opioid receptors in the brain, cytochrome 450 epoxygenases are released, suggesting a mechanism by which other pain-killers such as morphine and cannabinoids may also lower the perception of pain.
Article Link: http://www.nature.com/neuro/journal/v13/n3/full/nn.2497.html
About Integrated Tissue Dynamics (INTiDYN)
Integrated Tissue Dynamics, LLC, also known as INTiDYN, provides flexible and scalable research capabilities on behalf of pharmaceutical companies to detect chemical and structural changes in the skin that may cause the chronic numbness, pain and itch associated with a wide variety of afflictions such as diabetes, shingles, complex regional pain syndrome, carpal tunnel syndrome, sciatica, fibromyalgia, psoriasis, chemotherapy and even the unintended side effects caused by many drugs. Such afflictions and the associated neurological problems respond poorly to existing treatments.
Dr. Frank L. Rice, PhD
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