A rational biological source of pain in the skin of patients with fibromyalgia
In 2013, scientists at INTiDYN and clinicians at Albany Medical Center made a major discovery to provide a more certain diagnosis of fibromyalgia, a disease widely considered to be a central sensitization syndrome and in some instances has been attributed as a psychosomatic disorder. The findings demonstrated a peripheral vascular pathology that provided a rational source of the wide array of functional pathologies associated with fibromyalgia, including widespread pain, fatigue, and cognitive deficits.
Albrecht PJ, Hou Q, Argoff CE, Storey JR, Wymer JP, Rice FL (2013). Excessive Peptidergic Sensory Innervation of Cutaneous Arteriole-Venule Shunts (AVS) in the Palmar Glabrous Skin of Fibromyalgia Patients: Implications for Widespread Deep Tissue Pain and Fatigue. Pain Medicine, May 20. doi: 10.1111/pme.12139 [Epub ahead of print].
A description of the study for the general public can be found here.
To access the study at the National Library of Medicine (PubMed): http://www.ncbi.nlm.nih.gov/pubmed/23691965